Discussions on Toxic Traditional Chinese Medicine and New Perspectives
  
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DOI:10.4103/wjtcm.wjtcm_27_19
KeyWord:New toxicity testing strategy, safety, toxicity mechanism, traditional Chinese medicine
        
AuthorInstitution
Hong Liuab a.School of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou , China; b.Department of Pharmacology and Toxicology, Beijing Institute of Radiation Medicine, Beijing , China
Wei Zhoub b.Department of Pharmacology and Toxicology, Beijing Institute of Radiation Medicine, Beijing , China
Yue Gaoab a.School of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou , China; b.Department of Pharmacology and Toxicology, Beijing Institute of Radiation Medicine, Beijing , China
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Abstract:
      Along with the increase in the consumption of traditional Chinese medicine (TCM), the safety of TCM has dramatically attracted the attention and concern of the public. Here, we review previous studies, which focused mainly on the toxicity of toxic TCM and the interpretations for combination, to elaborate on advances and important issues existing in the safety evaluation of TCM, aiming to provide scientific advice for the clinical use. Moreover, we emphasize the importance of a safe evaluation system for TCM based on the material basis for toxicity, which integrates new toxicity testing strategy and is launched under the guidance of TCM theories in future researches.
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